Distance measurements between boron and carbon at natural abundance using magic angle spinning REAPDOR NMR and a universal curve.

Sensitive absorptive refocused scalar correlation NMR spectroscopy in solids.

A new two-dimensional NMR experiment is described which is suitable for obtaining magic angle spinning (MAS) scalar correlation spectra in solids. The new experiment has several advantages, including increased cross peak intensities, coupled with good suppression of the diagonal. Its utility is demonstrated via assignments of the carbon-13 MAS spectra of progesterone at natural abundance and of...

Longer-range distances by spinning-angle-encoding solid-state NMR spectroscopy.

A new spinning-angle-encoding spin-echo solid-state NMR approach is used to accurately determine the dipolar coupling corresponding to a C-C distance over 4 Å in a fully labelled dipeptide. The dipolar coupling dependent spin-echo modulation was recorded off magic angle, switching back to the magic angle for the acquisition of the free-induction decay, so as to obtain optimum sensitivity. The r...

Supporting Information: Proton-Selective 17O–1H Distance Measurements in Fast Magic-Angle-Spinning Solid-State NMR Spectroscopy for the Determination of Hydrogen Bond Lengths

Sensitivity enhancement and heteronuclear distance measurements in biological 17O solid-state NMR.

In this contribution we present a comprehensive approach to study hydrogen bonding in biological and biomimetic systems through 17O and 17O-1H solid-state NMR combined with density functional theory calculations of 17O and 1H NMR parameters. We explore the signal enhancement of 17O in L-tyrosine.HCl using repetitive double-frequency swept radio frequency pulses in solid-state NMR. The technique...

High-Resolution NMR of Anisotropic Samples With Spinning Away from the Magic Angle

High-resolution NMR of samples in the solid state is typically performed under mechanical sample spinning around an axis that makes an angle, called the magic angle, of 54.7 degrees with the static magnetic field. There are many cases in which geometrical and engineering constraints prevent spinning at this specific angle. Implementations of in-situ and ex-situ magic angle field spinning might ...